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Abstract (Word Count = 478)Context and purpose:  Cerebral palsy (CP) is the most common cause pediatric motor disability. It describes a group of disorders of the development of movement and posture resulting from a no progressive immature brain. This study aims to describe the factors of risks, the different clinical types and the functional profile of children with in the cities of  Cotonou and Parakou in Benin.Relevance: This study will provide epidemiological data useful for fighting cerebral palsy in Benin.Participants: The sample in our study included 115 children (mean age (standard deviation) = 7.7 (4.2) years; 66.1% of boys) diagnosed with paralysis brain, recruited from Community Based Rehabilitation Centers (RBC) and functional rehabilitation service in the North (Parakou) and South (Cotonou) of Benin.Methods: We conducted a cross-sectional study for descriptive purposes and analytic. Data collected through file review medical and interviews with mothers of children. The evaluation focused on neonatal and post-neonatal risk factors, clinical subtypes  according to the decision tree of the "Surveillance of Cerebral Palsy in Europe (SCEP) ", The severity of functional motor disability with the" Gross Motor Function Classification System (GMFCS) "and the" Manual Ability Classification System (MACS) ", then some comorbidities.Analysis: Our data was analyzed using SPSS software version 18.0. Chi2 tests Pearson and Anova were used for qualitative and quantitative variables. The threshold of significance was 5%.Results: More than half of the mothers had reported a delivery difficult with the notion of neonatal resuscitation of the newborn. 25% of children had a post-neonatal PC, mainly due to neuropaludism and secondary, meningitis. Most children have been severely impaired (72.2% as GMFCS III-V and 56.5% as MACS III - V). The period of attainment, the manual skill, the different forms of PCs and comorbidities are all factors related to the severity of the disability functional according to the GFMCS (p-values ​​<0.05).Conclusion:  Intrapartum risk factors, cerebral malaria, and Meningitis have been the major causes of PC under our skies. It would be interesting to confirm the results of this work through more studies longitudinal or transversal thrusts in the general population.Clinical implications: Follow-up of the pregnant woman, fight against malaria in pregnant women and children are potential sources of reduction in the prevalence of cerebral palsy in Benin.Keywords: Cerebral palsy, neurodevelopmental pathology, low income, sub-Saharan Africa.Sources of funding: No source of funding to declare.Ethical Approval: The Ethics Committee of the Department of Rehabilitation of National University Hospital  ( Cotonou, Republic of Benin) approved the study.